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Watch the Full Video at https://www.jove.com/v/55940/acute-vi.... Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats - a 2 minute Preview of the Experimental Protocol Jens K. Haumesser, Johanna Kühn, Christopher Güttler, Dieu-Huong Nguyen, Maximilian H. Beck, Andrea A. Kühn, Christoph van Riesen Charité University Medicine Berlin, Department of Neurology, Movement Disorder and Neuromodulation Unit Berlin; In this study, the methodology is presented on how to perform multi-site in vivo electrophysiological recordings from the hyperdirect pathway under urethane anesthesia. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments