The Noble Journey with Randy Schekman | Part I | Reason with science | Nobel prize | Cell biology скачать в хорошем качестве

The Noble Journey with Randy Schekman | Part I | Reason with science | Nobel prize | Cell biology

This is first part of the conversation with Randy Schekman. He is an investigator of the Howard Hughes Medical Institute and a Professor of Cell and Developmental Biology in the Department of Molecular and Cell Biology at the University of California at Berkeley. He was awarded the Nobel Prize in Physiology or Medicine in 2013 for his role in revealing the machinery that regulates the transport and secretion of proteins in our cells. He shares the prize with James E. Rothman of Yale University and Thomas C. Südhof of Stanford University. In this conversation we talk about his early career, membranes, exosomes, scientific publishing and Elife journal. Listen to part II:    • The Noble Journey | Randy Schekman | Part ...   Find more about Randy's work: http://mcb.berkeley.edu/labs/schekman/ Randy's biography: https://www.nobelprize.org/prizes/med... Episode links: Website: https://www.reasonwithscience.com/hom... Youtube:    • The Noble Journey with Randy Schekman | Pa...   Spotify: https://open.spotify.com/episode/3HkT... Apple podcast: https://podcasts.apple.com/us/podcast... Google podcast: https://podcasts.google.com/feed/aHR0... Follow Reason with Science: Website: https://www.reasonwithscience.com/ Youtube: https://www.youtube.com/channel/reaso... Spotify: https://open.spotify.com/show/5qFLGsP... Apple podcast: https://podcasts.apple.com/us/podcast... Google podcast: https://podcasts.google.com/feed/aHR0... Timetamps: 00:00:00 Introduction 00:01:08 Interest in microbes 00:05:27 Yeasts have feelings too! 00:06:24 What was already known about vesicular trafficking? 00:08:42 How do you envision a cell? 00:09:51 Your work to understand 'what is life'? 00:12:48 Formation of membranes for the origin of life 00:14:39 Why membranes are ideal for life! 00:15:48 Differences of membranes 00:17:07 The evolution of membranes 00:19:02 Starting the work on vesicular trafficking 00:23:09 Discovery of COPII complex 00:25:24 The specialty of COPII complex 00:26:30 Importance of vesicular trafficking for animal physiology 00:27:39 Understanding of gut feeling! 00:28:56 What has changed after Nobel prize? 00:30:30 Different cellular trafficking system 00:32:11 Exosomes and miR223 00:34:29 Problems with exosomes as therapeutics 00:35:08 Peer-review and scientific publishing 00:39:44 Genesis of Elife 00:44:05 Impact factor of Elife 00:46:35 Thank you! More Talks from Randy: TEDx on scientific publishing:    • Publishing important work in the life scie...   iBiology:    • Randy Schekman (HHMI & UCB) 1: Secretory P...   Nobel prize inspiration initiative lecture:    • Nobel Prize Inspiration Initiative lecture...   #reasonwithscience #nobelprize #cellbiology