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In this session from the 2025 Erdheim-Chester Disease Patient and Family Gathering, Dr. Francesco Pegoraro explores the connection between Erdheim-Chester Disease (ECD) and other blood disorders that may develop alongside it. As a clinical researcher and ECD Care Center clinician at Meyer Children’s Hospital in Florence, Italy, Dr. Pegoraro explains what concomitant diseases are, how they relate to ECD, and why ongoing monitoring is important. The session highlights research efforts to understand the genetic and clinical links between ECD and conditions such as myeloproliferative neoplasms, and how these relationships may influence both diagnosis and treatment. Patients and caregivers gain valuable insights into what to be aware of and how to advocate for comprehensive care. To learn more about Erdheim-Chester Disease and the ECD Global Alliance, visit: https://www.erdheim-chester.org/ The Erdheim-Chester Disease Global Alliance (ECDGA) does not provide medical advice, diagnoses, or treatments. All content is for informational purposes only. Please consult with a healthcare provider for medical concerns.