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This video explains the effect of ulcerative colitis on the human body. It illustrates important areas such as an overview of IBD and ulcerative colitis, symptoms, the disease’s behaviour, associated risk factors, the immunopathogenesis of the condition, current treatments and an interview portion about new treatments. In addition, the video provides sources that provide more information about ulcerative colitis and current research initiatives. This video was made by the McMaster Demystifying Medicine students Sarah Longo, Meghna Annapoorna, Yueyang Bao, Tamara Mohanavathanan and Andrea Krishnapillai. Copyright McMaster 2020. References: Fakhoury, M., Negrulj, R., Mooranian, A., & Al-Salami, H. (2014). Inflammatory bowel disease: Clinical aspects and treatments. Journal of Inflammation Research,7, 113–120. https://doi.org/10.2147/JIR.S65979 Gajendran, M., Loganathan, P., Jimenez, G., Catinella, A. P., Ng, N., Umapathy, C., Ziade, N., & Hashash, J. G. (2019). A comprehensive review and update on ulcerative colitis,. Disease-a-Month, 65(12), 100851. https://doi.org/10.1016/j.disamonth.2... Lynch, W. D., & Hsu, R. (2020). Ulcerative Colitis. StatPearls. http://www.ncbi.nlm.nih.gov/books/NBK... Ordás, I., Eckmann, L., Talamini, M., Baumgart, D. C., & Sandborn, W. J. (2012). Ulcerative colitis. Lancet (London, England), 380(9853), 1606–1619. https://doi.org/10.1016/S0140-6736(12... Sanchez-Muñoz, F., Dominguez-Lopez, A., & Yamamoto-Furusho, J. K. (2008). Role of cytokines in inflammatory bowel disease. World Journal of Gastroenterology: WJG, 14(27), 4280–4288. https://doi.org/10.3748/wjg.14.4280 Surgery for Ulcerative Colitis. (n.d.). Crohn’s & Colitis Foundation. Retrieved March 1,2020, from https://www.crohnscolitisfoundation.o... Wallace, K. L., Zheng, L.-B., Kanazawa, Y., & Shih, D. Q. (2014). Immunopathology of inflammatory bowel disease. World Journal of Gastroenterology: WJG, 20(1),6–21. https://doi.org/10.3748/wjg.v20.i1.6