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Naltrexone: Not a Primary MAT - but Still Worth Knowing Presented by: David R. Gastfriend, MD, DFASAM Event Date: 03-21-2018 Event Description: Oral naltrexone (NTX-PO) is a potent blocker at brain opioid receptors, so it was a natural consideration as a medication in addiction treatment (MAT) for Opioid Use Disorder (OUD). For most OUD patients, however, studies have not found NTX-PO to be any better than placebo or non-medication treatment – due to poor adherence by patients. Nevertheless, it is still used for patients whose pill-taking can be regularly monitored, for detoxification and induction onto extended-release naltrexone, and for patients who have completed MAT but encounter new stressors for which they may want temporary protection from relapse. View Webinar | View Presentation Materials This training is supported by the Florida Department of Children and Families Office of Substance Abuse and Mental Health.