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The College of Engineering at NC State continued its Applied AI Futures Seminar Series by welcoming Dr. Sergei Kalinin, Weston Fulton Chair Professor, University of Tennessee, Knoxville (UTK); Chief Scientist for Artificial Intelligence and Machine Learning for Physical Sciences, Pacific Northwest National Laboratory (PNNL). His research focuses on the applications of machine learning and artificial intelligence methods in materials synthesis, discovery and optimization and in automated experiment and autonomous imaging and characterization workflows in scanning transmission electron microscopy and scanning probes for applications including physics discovery, atomic fabrication, as well as mesoscopic studies of electrochemical, ferroelectric and transport phenomena via scanning probe microscopy. When at ORNL, he led several major programs integrating ML and physical sciences and instrumentation, including the Institute for Functional Imaging of Materials (IFIM 2014-19), the first program in the Department of Energy integrating ML and physical sciences, and the microscopy effort in INTERSECT program that realized first ML-controlled scanning probe and electron microscopes.