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Official Ninja Nerd Website: https://ninjanerd.org You can find the NOTES and ILLUSTRATIONS for this lecture on our website at: https://www.ninjanerd.org/lecture/aut... Ninja Nerds! In this high-yield pharmacology lecture, Professor Zach Murphy presents a detailed and visually engaging overview of Adrenergic Agonists, emphasizing their mechanisms of action, receptor selectivity, and clinical relevance. This lecture will help you master the key sympathomimetic agents and understand how they modulate the sympathetic nervous system. We begin with a concise review of adrenergic physiology, covering the roles of alpha (α1, α2) and beta (β1, β2, β3) adrenergic receptors and their locations in various organ systems. From there, we explore both direct-acting and indirect-acting adrenergic agonists, including: • Endogenous catecholamines: Epinephrine, Norepinephrine, Dopamine • Synthetic agents: Phenylephrine, Clonidine, Dobutamine, Albuterol, Isoproterenol • Indirect-acting agents: Amphetamines, Cocaine, Tyramine Each drug is discussed in detail, covering: • Mechanism of action: Receptor subtype selectivity and downstream effects • Physiologic effects: Cardiovascular, pulmonary, metabolic, and ocular responses • Clinical indications: Shock states, asthma, bradycardia, nasal congestion, ADHD • Adverse effects: Hypertension, tachyarrhythmias, anxiety, ischemia, tolerance The lecture includes comparative tables, diagrams, and clinical scenarios to help solidify your understanding and differentiate between similar agents. Whether you’re reviewing for your pharmacology course or brushing up on clinical applications, this lecture will give you a solid grasp of adrenergic agonists and their therapeutic uses. Enjoy the lecture and support us below! Table of Contents: 0:00 Lab 0:07 Adrenergic Agonists Introduction 1:06 Adrenergic Neurons and Receptors 19:32 Adrenergic Target Organ Effects 30:34 Alpha 1 Agonists 39:38 Alpha 2 Agonists 47:48 Beta 1 Agonists 51:42 Beta 1 + 2 Agonists 56:19 Beta 2 Agonists 1:02:47 Beta 3 Agonists 1:04:07 Alpha + Beta Agonists 1:13:17 Epinephrine + Dopamine 1:22:30 Norepinephrine Graphical Representation 1:29:48 Epinephrine Graphical Representation 1:34:49 Isoproterenol Graphical Representation 1:39:11 Adrenergic Agonists Practice Problems 1:45:20 Comment, Like, SUBSCRIBE! Supplemental Lecture: Neurology | Adrenergic Receptors -- • Neurology | Adrenergic Receptors Pharmacology Source: Whalen, Karen. Lippincott Illustrated Reviews: Pharmacology (Lippincott Illustrated Reviews Series). Wolters Kluwer Health. Kindle Edition. 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media / ninjanerdlectures / ninjanerdlectures / ninjanerdlectures https://x.com/ninjanerdsci/ / ninja-nerd 💬 Join Our Community Discord: / discord #ninjanerd #pharmacology #AdrenergicAgonists