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Presented By: Guillermo Moreno-Sanz, PhD Speaker Biography: Dr. Guillermo Moreno-Sanz has been involved in cannabinoid research for over 20 years and has authored more than 30 scientific articles and 3 patents describing the role of the endocannabinoid system in the control of pain. He holds a PhD in Neuroscience from Complutense University of Madrid, Spain. He received a Fulbright scholarship to complete his education at the University of California, Irvine, where he developed a new class of cannabinoid analgesics. Since 2020 he acts as Scientific Director of Khiron Europe, a distributor of cannabis-based medicinal products, and Leva Clinic, a telehealth clinic in the UK specialized in treating chronic painful conditions with digital, non-pharmacological interventions. Webinar: NHS-Reimbursed Cannabis Flowers for Cancer Palliative Care: the Mike Roberts Case Report Webinar Abstract: Chemotherapy-induced nausea and vomiting (CINV) is a debilitating side effect of cancer treatment, affecting many patients. Cannabinoid agonists, such as nabilone and Δ9-tetrahydrocannabinol (THC), the main psychoactive component of Cannabis sativa L., have shown efficacy as antiemetics. Here, we report the case of Michael Roberts (MR), who we believe is the first British patient reimbursed by the National Health Service (NHS) England for the cost of medicinal cannabis flowers to manage CINV. Medical data were obtained from NHS records and individual funding request (IFR) forms. Patient-reported outcome measures (PROMs) were collected using validated questionnaires as part of the standard of care at the specialized private clinics where the prescription of medicinal cannabis was initiated. The patient presented with rectosigmoid adenocarcinoma with lung metastases. He received FOLFIRI (folinic acid, fluorouracil, and irinotecan) chemotherapy and underwent an emergency Hartmann's procedure with subsequent second-line FOLFOX (folinic acid, fluorouracil, and oxaliplatin) chemotherapy and lung ablation. MR reported severe nausea and vomiting associated with the initial FOLFIRI treatment. Antiemetics metoclopramide and aprepitant demonstrated moderated efficacy. Antiemetics ondansetron, levomepromazine, and nabilone were associated with intolerable side effects. Inhalation of THC-predominant cannabis flowers in association with standard medication improved CINV, anxiety, sleep quality, appetite, overall mood, and quality of life. Our results add to the available evidence suggesting that medicinal cannabis flowers may offer valuable support in cancer palliative care integrated with standard-of-care oncology treatment. The successful individual funding request in this case demonstrates a pathway for other patients to gain access to these treatments, advocating for broader awareness and integration of cannabis-based medicinal products in national healthcare services. Earn PACE Credits: 1. Make sure you’re a registered member of Labroots (https://www.labroots.com/) 2. Watch the webinar on YouTube or on the Labroots Website (https://www.labroots.com/ms/webinar/n...) 3. Click Here to get your PACE credits (Expiration date – April 16, 2027): (https://www.labroots.com/credit/pace-... Labroots on Social: Facebook: / labrootsinc Twitter: / labroots LinkedIn: / labroots Instagram: / labrootsinc Pinterest: / labroots SnapChat: labroots_inc