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Timestamps: 00:00 - Introduction: The PDA Problem in Preterm Infants 00:15 - Presenter Introduction: 01:55 - Overview of the AAP guidelines 21:30 - Experts comments, Discussion, Q and A About the Speakers: Presenter: Dr. Anum Shah Mentor: Dr. Hussnain Mirza Subscribe to APPNA Peds for more expert pediatric content and guideline updates. #AAPGuidelines #PDA #Neonatology #Pediatrics #PretermInfant A new consensus report from the American Academy of Pediatrics (AAP) is fundamentally shifting the approach to managing Patent Ductus Arteriosus (PDA) in preterm infants. This APPNA Peds journal club, presented by Dr. Anum Shah and mentored by Dr. Hussnain Mirza, provides a critical analysis of these new guidelines. Join a panel of neonatologists and pediatric specialists as they debate the move away from routine early intervention towards a more conservative "wait-and-see" approach. The discussion focuses on a central question: When does the evidence support medical or surgical intervention for a hemodynamically significant PDA (HSPDA), and when is observation superior? This session covers: ► Detailed breakdown of the 2024/2025 AAP consensus report recommendations. ► The evidence for delaying treatment beyond two weeks of life. ► New objective criteria for defining a hemodynamically significant PDA (HSPDA) using echocardiography. ► Comparison of treatment options: Ibuprofen, Indomethacin, Paracetamol, transcatheter device closure (Piccolo device), and surgical ligation. ► Real-world application of guidelines in high-resource vs. low-resource settings. This video is essential for neonatologists, pediatric residents, fellows, and advanced practice providers seeking to integrate the latest evidence on PDA management into their clinical practice. TIMESTAMPS: (Note: Please verify these times against your video file. These are based on the content flow.) 00:00 - Introduction & The Controversy of PDA Management 01:55 - Overview: Key Changes in the New AAP Guidelines 05:20 - The Rationale for Change: Spontaneous Closure Rates 06:30 - Defining Hemodynamically Significant PDA (HSPDA): Beyond Echo Size 09:30 - Proposed New PDA Scoring System and its Limitations 10:30 - Guideline Recommendation: Prophylactic Treatment Not Recommended 11:30 - Pharmacological Therapy: Ibuprofen vs. Indomethacin vs. Paracetamol 13:10 - Guideline Recommendation: Expectant (Conservative) Management Explained 14:20 - Surgical Closure vs. Transcatheter Device Closure (Piccolo Device) 19:15 - Summary of Six Key Recommendations from the AAP Report 21:30 - Start of Q&A and Expert Panel Discussion 24:00 - Q&A: Why wait two weeks if the baby shows symptoms early? 30:10 - Q&A: Challenges in applying guidelines in low-resource settings (NEC, sepsis risk) 33:00 - Q&A: Choice of medication (Ibuprofen vs. Paracetamol) for feed intolerance 36:00 - Q&A: Does delaying treatment reduce medication effectiveness later? 38:40 - Discussion: Importance of point-of-care ultrasound (POCUS) in decision making 45:00 - Experience Sharing: Device closure experiences in Pakistan and the US 01:04:00 - Discussion: Clinical judgment vs. protocol when echo access is limited #PDA #AAPGuidelines #Neonatology #PretermInfant #Pediatrics Welcome to the APPNA Pediatrics Channel! We bring you expert insights, medical education, health advocacy, and career guidance, all in one place. Whether you’re a medical professional, student, or a parent seeking reliable health information, you’re in the right place. 🌟 About Our Videos: Our content covers a wide range of topics, including: Medical education: USMLE preparation, residency tips, and board exam guidance Health advocacy: Maternal and child health, gun violence, and the opioid crisis Pediatric health: Newborn care, immunization schedules, and developmental milestones Career guidance: Mentorship, research tips, and private practice setup Innovative health education for families 🎯 Why Subscribe? Join our growing community of learners and advocates dedicated to improving healthcare and empowering individuals with actionable knowledge. 📚 Connect and Stay Updated: Watch Our Other Videos & Resources 1 / @appnapediatrics 2 / @appnapediatrics 3 • Lectures 4 / @appnapediatrics 5 https://appnapeds.org 6 https://appnapeds.org/links/ 7 https://appnapediatrics.org/ 8 / posts