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Compared to rodents and non-human primates, large animal models such as dogs and miniature pigs offer several advantages. They strike a balance between genetic, physiological, and structural similarities to humans while maintaining relatively low experimental costs, making them widely used in research and medical applications. These models are particularly effective in cardiovascular, neurological, dermatological, inflammatory immunity, and endocrine/metabolism research. For example, the Medicilon Large Animal Pharmacodynamic Research Service Platform supports a wide array of disease models. Including but not limited to metabolic diseases (such as obesity, diabetes, and hyperuricemia), cardiovascular diseases (such as thrombosis, stroke, and atherosclerosis), inflammatory and immune diseases (such as arthritis, osteoporosis, and psoriasis), or other diseases. This broad coverage addresses almost all major disease areas relevant to current drug development. Large animal models can simulate the pharmacokinetic and pharmacodynamic characteristics of the human body, enabling researchers to better understand drug absorption, distribution, metabolism, and excretion processes. Learn more: https://www.medicilon.com/services/la... These models are also ideal for safety assessment, providing effective evaluations on organs and systems. Here at Medicilon, we offer more than just standard disease model development. We also specialize in customizing complex disease models to meet the unique needs of clients. From drug screening and efficacy evaluation to safety assessments, the large animal pharmacodynamic research service platform offers end-to-end services design to accelerate the drug development process.