PRIMO: Bioengineering platform for custom cell microenvironments in vitro скачать в хорошем качестве

PRIMO: Bioengineering platform for custom cell microenvironments in vitro

One of the challenges confronting cell biologists in vitro is to work with controlled and reproducible microenvironments to more efficiently study living cells and model diseases. PRIMO contactless and maskless photopatterning platform allows to engineer custom in vitro microenvironments and fine-tune their mechanical and biochemical properties, at the micrometer scale with high flexibility and reproducibility. PRIMO combines a contactless and maskless photolithography system controlled by a dedicated software (named “Leonardo”) and a specific photoactivatable reagent (PLPP). As a photopatterning system, PRIMO can be used for microfabrication and hydrogel structuration to create microstructured substrates with controlled topography and stiffness. Additionally, the combined action of U (λ=375nm) and PLPP makes it possible to perform micropatterning and generate, in only a few seconds, any multi-protein pattern on standard cell culture substrates (flat or structured, stiff or soft). Leran more on PRIMO, visit: www.alveolelab.com