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Watch the Full Video at https://www.jove.com/v/52656/methods-.... Methods for Culturing Human Femur Tissue Explants to Study Breast Cancer Cell Colonization of the Metastatic Niche - a 2 minute Preview of the Experimental Protocol Zachary S. Templeton, Michael H. Bachmann, Rajiv V. Alluri, William J. Maloney, Christopher H. Contag, Bonnie L. King Stanford University School of Medicine, Department of Pediatrics; Stanford University School of Medicine, Department of Orthopaedic Surgery; Protocols are described for studying breast cancer cell migration, proliferation and colonization in a human bone tissue explant model system. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments