Basic Reproduction Number, R0 скачать в хорошем качестве

Basic Reproduction Number, R0

Basic reproduction number R0 R0 tells you the average number of people who will catch a disease from one contagious person. Spread into a population with no previous exposure to the antigen Assumes no pre-existing immunity through exposure or vaccination R0 = 1 R0 greater than 1 R0 less than 1 Determining factors of R0 Infectious period How long an infection is contagious for Flu, typically up to 8 days Flu in children, up to two weeks Longer an infection is contagious for, the higher the R0 Contact rate How many people an infected person comes into contact with E.g. R0 will be lower if a person stays at home, higher if they are out and about Mode of transmission Shedding pottential Rapid speed if airborne, flu or measles. No physical contact or fomite necessary Slower if transmitted by body fluids, e.g. Ebola, Hepatitis B, C, or HIV, Influenza Droplet R0 = 0.9 – 2.1 2009 Droplet R0 = 1.4 – 1.6 Hepatitis C Body fluids R0 = 2 Ebola Body fluids R0 = 2 1918 Droplet R0 = 1.4 – 2.8 HIV Body fluids R0 = 4 Smallpox Droplet R0 = 3.5 - 6 Mumps Droplet R0 = 4-7 Pertussis Droplet R0 = 5.5 Measles Airborne R0 = 18 Super-spreaders 20/80 rule 20% of infected individuals are responsible for 80% of transmissions Individual reproductive number