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This episode features Matthew Baggott of Tactogen Inc. and will explore entactogens, which are drugs like MDMA, 2C-B, and Methalone We start with setting a basic framework for what an entactogen is and a few example drugs, before exploring the complexities in their various effects, mechanisms of action, and both the legislative and technical process of the development of novel or new entactogenic drugs. -LINKS- For links to Baggot's work, full show notes, and to access an audio-only stream of this episode, head to https://bit.ly/ATTMind177 **Full Topics Breakdown Below** --- SUPPORT THIS PODCAST — ► Patreon: / jameswjesso ► PayPal Donation: https://www.paypal.com/biz/fund?id=38... ►Crypto Donations: https://www.jameswjesso.com/bitcoin/ ► Merchandise: https://www.jameswjesso.com/shop/ ► More options: https://www.jameswjesso.com/support/ ► Newsletter: https://www.jameswjesso.com/newsletter ► Telegram Channel: https://t.me/jameswjesso ************** Episode Breakdown (0:00) Opening (2:44) Guest Bio (4:06) Patreon thanks | Support The Show (5:42) Interview begins (6:31) What is an entactogen and what does it do? | The difference between entactogens and psychedelics (8:37) A short discussion about 2C-B (11:47) A list of different entactogens (15:30) r-MDMA vs s-MDMA (19:48) Methalone, aka bk-MDMA (21:52) 3-MMC and 4-MMC: patents, development, and legality (23:13) Why Schedule 1 makes drug development difficult (25:02) The qualities they are trying to design OUT of new entactogen drugs (pt1) (26:31) “The loss of magic” with MDMA (33:11) Serotin transporters and MDMA neuro-oxidization (36:27) Using NAC to bring back the MDMA magic | enhanced plasticity, antioxidants, and homeostasis (44:13) The qualities they are trying to design OUT of new entactogen drugs (pt2) (48:52) Why we need “take home” entactogenic drugs (53:20) Can a drug still be medicine if it’s fun, too? (58:13) The process of justifying off-label MDMA prescriptions (1:03:01) Will there be a moral backlash against the development of “good feel” drugs? (1:11:10) The negative social consequences of prohibitionist law enforcement (1:15:58) We can’t just give people psychedelics and expect society will get better (1:18:46) Problematic moves in the psychedelic biotech industry (1:25:01) Psychedelic Patent Trolling (1:32:15) How Tactogen is trying to give back to psychedelic users (1:44:16) Increasing access to health care, not just to psychedelic substances (1:49:40) Follow-up link and contact details (1:51:25) closing ************** --- SUPPORT THIS PODCAST — Patreon: / jameswjesso Donations: https://www.paypal.me/JWJesso Merchandise: https://www.jameswjesso.com/shop/ More options: https://www.jameswjesso.com/support/ Newsletter: https://www.jameswjesso.com/newsletter ▻ James' BOOKS ‣ Decomposing The Shadow: https://www.jameswjesso.com/decomposi... ‣ The True Light Of Darkness: https://www.jameswjesso.com/true-ligh... ▻ PRODUCTS: https://www.jameswjesso.com/shop-2/