20: QSAR Toolbox: Activation as a result of metabolism скачать в хорошем качестве

20: QSAR Toolbox: Activation as a result of metabolism

This video tutorial demonstrates the evaluation of a metabolically activated chemical using the QSAR Toolbox. Abiotic and biotic transformations of chemicals play a crucial role in hazard assessment. In this example, the potential skin sensitisation effect of a chemical is evaluated, considering its metabolic activation. The tutorial explores the use of relevant profilers and simulators, including auto oxidation and skin metabolism, to assess the chemical and its metabolites. By analysing the profiling results and understanding protein binding alerts, users can determine the chemical’s potential impact. For technical questions, contact the QSAR Toolbox helpdesk: https://qsartoolbox.freshdesk.com/sup... For questions on regulatory acceptance of QSAR Toolbox results within EU legislation in ECHA's remit, contact the ECHA helpdesk: https://echa.europa.eu/contact More on the QSAR Toolbox: https://qsartoolbox.org This video is made in collaboration with the Laboratory of Mathematical Chemistry (LMC, Burgas, Bulgaria): https://oasis-lmc.org. ************** Subscribe to our channel: https://bit.ly/321VQgE Subscribe to our Safer Chemicals Podcast: https://echa.europa.eu/podcasts Subscribe to our news: https://echa.europa.eu/subscribe Follow us on: *Twitter:   / eu_echa   *Facebook:   / euecha   *LinkedIn:   / european-chemicals-agency   Visit our website: https://echa.europa.eu/