Wound Healing - Phase 3 - Proliferative скачать в хорошем качестве

Wound Healing - Phase 3 - Proliferative

In this video, we dive into the proliferative phase of wound healing—a critical stage in the complex process of tissue repair. Whether you’re a medical student, healthcare professional, or someone interested in the science of healing, this video provides a clear, step-by-step breakdown of what happens in the body during this essential phase of wound recovery. 🔬 What is the Proliferative Phase? The proliferative phase is the second major phase of wound healing, following the inflammatory phase. It typically begins around day 3 to day 5 post-injury and lasts for several days. This phase is marked by the activation and coordination of fibroblasts, endothelial cells, and keratinocytes to rebuild damaged tissue. 📌 Key Events Covered in This Video: Fibroblast migration and collagen synthesis (primarily type III collagen) Angiogenesis: the formation of new blood vessels through endothelial cell proliferation Granulation tissue formation Epithelialization: resurfacing of the wound bed by keratinocytes Extracellular matrix (ECM) deposition and the scaffold for further healing 💡 Basic Science You’ll Learn: The role of growth factors like VEGF, FGF, TGF-β, and PDGF How oxygen tension and hypoxia-inducible factors (HIFs) stimulate capillary sprouting The transition from type III to type I collagen Why angiogenesis is vital for nutrient delivery and immune cell access 🩹 Clinical Relevance: Why wounds fail to heal in diabetic patients or individuals with vascular disease What an unhealthy or stalled proliferative phase looks like How this phase informs surgical wound care, dressings, and grafting decisions #WoundHealing #ProliferativePhase #GranulationTissue #Angiogenesis #WoundCare #BasicScience #MedicalEducation #SurgicalHealing #Physiology #WoundRepair