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Cystic fibrosis (CF) is a permanent condition. People with CF look like everyone else, but have health problems. Cystic fibrosis does not affect the brain or how smart a person is. Children with CF go to school, play sports, and get their driver’s license. Adults go to college, have successful jobs, live on their own, and get married. CF does not affect every person the same way so it’s hard to say how mild or severe the condition may be. There is not yet a cure, but there are many treatments. People with CF are living longer, better-quality lives than ever before. CF is caused by genes that do not work properly. These genes are inherited from each parent. When healthy, the CF gene makes a protein called CFTR. This protein is found in the cells of many organs, like the lungs and the pancreas. CFTR stands for “cystic fibrosis transmembrane regulator”. This protein helps the flow of chloride and sodium (salt and water) in and out of cells. When the CF gene is changed (called a mutation), the CFTR protein in the cells does not work properly. This causes the salt balance in the body to be unequal and leads to very thick mucus. This mucus then blocks the passages in certain parts of the body. Lungs/Sinuses: The CF lung is dry and the thick mucus can’t easily be moved or coughed out. In time, the thick mucus builds up and clogs the airways. This can lead to infections and inflammation (swelling) in the lungs. Thick mucus in the sinuses can also cause infections. Digestion/Growth: Thick mucus blocks the digestive tract and pancreas. This stops digestive enzymes from getting into the intestines. Enzymes are needed to break down food, which provides nutrients to help people grow and stay healthy. Liver, bone health, and reproductive systems: Liver disease, CF-related diabetes, bone mineral issues, and low vitamin levels can also occur. Most men with CF are unable to naturally conceive a child. However, methods now exist to help this problem. Women with CF may become pregnant, but have special health concerns. They should talk to their doctor if thinking about having a baby. Support my channel by contributing at / clinicalbiochemistrybydrpkprabhakar Join this channel to get access to perks: / @clinicalbiochemistry