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ViralZone and the Revolution in 3D Virus Structure

ViralZone (https://viralzone.expasy.org/) is a SIB Swiss Institute of Bioinformatics web resource for all viral genera and families. It provides molecular biology information on all kind of viruses, and bridges knowledge to virus or sequence databases. For each virus or family page, ViralZone provides easy access to the corresponding UniProtKB/Swiss-Prot (https://www.uniprot.org/) and GenBank viral protein entries. It also contains virion and genome images. This video introduces the structural knowledge of viral proteins and the main tools available to study them. The video was recorded live during the SIB course streamed on March 27, 2025. Target audience: This course is addressed to students, postdocs, and researchers, from any scientific environment (academia, facilities, companies, etc.) interested in viral proteins. Speaker: Philippe Le Mercier, ViralZone Resource Manager, Swiss-Prot group Any question about this talk? Contact ViralZone (https://web.expasy.org/contact.html?s...) 00:00 Introduction 02:45 Introduction to structural virology 13:26 Modeling resources 27:36 Virus model databases 42:02 AF3 shed light on reovirus capsids 57:08 Capsid assembly tools 01:05:08 Structural phylogenetics