PRR: Toll-like Receptors (TLRs) – Innate Immunity and Signaling Pathways - IMMUNOLOGY скачать в хорошем качестве

PRR: Toll-like Receptors (TLRs) – Innate Immunity and Signaling Pathways - IMMUNOLOGY

In this lecture, we explore the Toll-like receptors (TLRs), a crucial family of pattern recognition receptors (PRRs) that enable innate immune cells to detect pathogens and tissue damage. 📌 What you will learn in this video: -) PAMPs and DAMPs: how the innate immune system detects pathogens and damage -) The structure of TLRs: LRR domains, transmembrane and TIR domains -) Positioning of TLRs: plasma membrane vs endosomes -) Ligands of TLRs: bacterial, viral, and fungal components -) Key receptors: TLR-1, TLR-2, TLR-4, TLR-5, TLR-6, TLR-3, TLR-7, TLR-8, TLR-9 -) TLR signaling pathways: MyD88/MAL, TRIF/TRAM, IRF and NF-κB activation -) Clinical and functional implications in infection and immunity 📚 Who is this video for? -) Medical and biomedical students preparing for exams in immunology, microbiology, and pathology (university level-video) -) Educators and lecturers, who can use this resource as classroom support -) Anyone passionate about immunology and molecular medicine ✅ Stay connected 🔔 Subscribe to Agorà Biomedical Sciences for more videos on Immunology, Anatomy, and Physiology 👍 Like this video if you found it helpful 💬 Share your questions or teaching suggestions in the comments 🔎 Optimized hashtags and keywords #Immunology #InnateImmunity #TLRs #TollLikeReceptors #PRRs #PAMPs #DAMPs #NFkB #IRF #AgoràScienzeBiomediche #MedicalEducation #ImmunologyLecture