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#drnajeeb #medicines #mutations #mutation #biomolecules #biology #dna Mutation | Types of Mutations | DNA Genetics | Part 2👨⚕️ Like this video? Sign up now on our website at https://www.DrNajeebLectures.com to access 1000+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $59 ONLY! Sign up now on our website at https://members.drnajeeblectures.com/... --------------------------------------------------------------------------------------------------------------------------- Why sign up for premium membership? Here's why! Membership Features for premium website members. 1. More than 1000+ Medical Lectures. 2. Basic Medical Sciences & Clinical Medicine. 3. Mobile-friendly interface with android and iOS apps. 4. English subtitles and new videos every week. 5. Download option for offline video playback. 6. Fanatic customer support and that's 24/7. 7. Fast video playback option to learn faster. 8. Trusted by over 2M+ students in 190 countries. --------------------------------------------------------------------------------------------------------------------------- ▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬ 00:00:00 Continuing The Previous Lecture 00:01:42 Continuous Principle 00:08:40 Point Mutations 00:09:41 Types Of Point Mutations 00:10:07 Transitions 00:12:46 Transconversions 00:16:29 Silent Mutations 00:17:36 Spacer Dna 00:19:09 Mutations In Interons 00:22:20 3rd Nucleotide Nitrogenous Base 00:25:00 Missense Mutations 00:26:49 Types Of Missense Mutations 00:27:22 Acceptable Mutations 00:29:16 Partially Acceptable Mutations 00:30:34 Unacceptable Mutations 00:34:28 Nonsense Mutations 00:38:33 Frameshift Mutations 00:43:42 Garbled Proteins 00:45:00 Simple Deletions 00:55:32 Translocation Mutations 01:00:14 Mutations In Promoter Box 01:02:50 Mutations Resulting In Abnormal Interon Removal And Exon Splicing 01:09:45 Insertional Mutations 01:12:11 Trinucleotide Repeat Mutations 01:17:19 Dynamic Mutations 01:17:54 Phenomenon Of Anticipation --------------------------------------------------------------------------------------------------------------------------- Types of Mutations There are various schemes for classification of different kind of mutations. Depending on: A. The Type of Cell Involved 1. Somatic mutations • Mutations that are in the somatic tissues of the body. • Mutations are not transmitted to progeny. • The extent of the phenotypic effect depends upon whether the mutation is dominant or recessive (dominant mutations generally have a greater effect). • The extent of the phenotypic effect depends upon whether it occurs early or late in development (early arising mutations have a greater effect). 2. Germinal mutations • Mutations that are in the germ tissues of the body. • Mutations may be transmitted to progeny • Dominant mutations are seen in first generation after the mutation occurs • If a female gamete containing an X-linked mutation is fertilized, the males will show the mutant phenotype • Recessive mutations will only be seen upon the chance mating with an individual carrying the recessive allele too; thus, the recessive mutation may remain hidden for many generations B. Mode of Origin (1) Spontaneous mutations The spontaneous mutations occur suddenly in the nature and their origin is unknown. They are also called “background mutation” and have been reported in many organisms such as, Oenothera, maize, bread molds, microorganisms (bacteria and viruses), Drosophila, mice, man, etc. (2) Induced mutations Besides naturally occurring spontaneous mutations, the mutations can be induced artificially in the living organisms by exposing them to abnormal environment such as radiation, certain physical conditions (i.e., temperature) and chemicals. C. Direction of Mutation According to their mode of direction following types of mutations have been recognized: --------------------------------------------------------------------------------------------------------------------------- Join this channel to get access to perks: Sign up now on our website at https://members.drnajeeblectures.com/... / @doctornajeeb Follow us on Facebook :- / drnajeeb Follow us on Instagram :- / drnajeeblectures