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A varicocele is when veins become enlarged inside your scrotum (the pouch of skin that holds your testicles). Dr. Sarah Vij joins the Urology Care Podcast to discuss what to know about this condition. Dr. Vij is a urologist with the Cleveland Clinic in Cleveland, Ohio. #UrologyCareFoundation #AUA #PatientEducation The Urology Care Foundation is the official foundation of the American Urological Association. We support urologic research and strive to provide the most current, comprehensive and reliable urologic health information for patients and the public. A varicocele is when veins become enlarged inside your scrotum (the pouch of skin that holds your testicles). These veins are called the pampiniform plexus. Out of one hundred males, ten to fifteen have varicocele. It is like getting a varicose vein in your leg. The male reproductive system makes, stores, and moves sperm. The scrotum is the sac of skin that holds the testicles (testes). Sperm and the hormone testosterone are made in the testicles. Sperm mature while moving through a coiled tube (the epididymis) behind each testicle. Sperm travel to the prostate from each epididymis using a tube called the vas deferens. When you ejaculate, seminal fluid mixes with sperm in the prostate to form semen. The semen travels through the urethra and comes out the end of your penis. Varicoceles are when the pampiniform plexus veins in the scrotum become enlarged. These veins are like varicose veins (twisted, swollen veins, found in the leg.) Varicoceles form during puberty. They can grow larger and you may notice them more over time. Varicoceles are more common on the left side of the scrotum. This is because the male anatomy is not the same on both sides. Varicoceles can exist on both sides at the same time, but this is rare. About 10 to 15 boys out of 100 have a varicocele. Most of the time, varicoceles cause no problems and are harmless. Less often varicoceles can cause pain, problems fathering a child, or one testicle to grow slower or shrink.