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Watch the Full Video at https://www.jove.com/v/50400/implemen.... Implementing Dynamic Clamp with Synaptic and Artificial Conductances in Mouse Retinal Ganglion Cells - a 2 minute Preview of the Experimental Protocol Jin Y. Huang, Klaus M. Stiefel, Dario A. Protti University of Sydney , Discipline of Biomedical Science, School of Medical Sciences, Sydney Medical School and Bosch Institute; University of Western Sydney, The MARCS Institute; University of Sydney , Discipline of Physiology, School of Medical Sciences, Sydney Medical School and Bosch Institute; This video article illustrates the set-up, the procedures to patch cell bodies and how to implement dynamic clamp recordings from ganglion cells in whole-mount mouse retinae. This technique allows the investigation of the precise contribution of excitatory and inhibitory synaptic inputs, and their relative magnitude and timing to neuronal spiking. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments