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Cone Reconstruction for Ebstein Anomaly

Dr. Patrick O’Leary, a Consultant in Pediatric Cardiology at Mayo Clinic in Rochester, MN, reviews his article appearing in the December 2021 issue of Mayo Clinic Proceedings, where he notes tricuspid cone reconstruction for Ebstein Anomaly was associated with reduce right ventricular size and increased right ventricular fractional area change. When a right ventricular injection of bone marrow derived stem cells was given during cone reconstruction, the increase in ventricular fractional area was augmented. In addition, stem cell injection was associated with improved left ventricular ejection fraction at 6 months post-cone reconstruction. This is evidence of a favorable interventricular interaction and these findings provide motivation for continued investigation into the potential benefits of stem cell therapy in Ebstein Anomaly and other congenital cardiac malformations. Available at: https://mayocl.in/3z29Ruv