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This is a clip from Ep. 166 (Endometriosis) of Cole and I discussing the use of add-back therapy when putting a patient on a GnRH agonist such as leuprolide depot. Some examples of add-back therapy options are below: 1. Norethindrone 5 mg (Aygestin) 2. Oral conjugated equine estrogens 0.625 mg (Premarin) plus oral norethindrone 5 mg (Aygestin) 3. Transdermal estradiol (Vivelle-Dot) 25 μg twice weekly plus oral medroxyprogesterone acetate 5 mg/day (provera) 4. Oral estradiol 2 mg/day plus oral norethindrone acetate 1 mg/day Listen to the entire episode on Spotify by visiting the link below: https://open.spotify.com/episode/4tfG... Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below: www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - [email protected] Cole - [email protected] Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.