Autologous Regenerative Treatment for Knee Cartilage Degeneration скачать в хорошем качестве

Autologous Regenerative Treatment for Knee Cartilage Degeneration

THIS MATERIAL IS FOR EDUCATIONAL PURPOSES, AIMED AT DOCTORS WHO HAVE OBTAINED THE CERTIFICATE OF PARTICIPATION IN THE SEFFIGYN™ BASIC COURSE For online courses https://seffiline.com/ For more informations https://sefficare.com/ Autologous Regenerative Treatment for Knee Cartilage Degeneration Paolo Trentani MD - Italy This material is for educational purposes, aimed at doctors who have obtained the certificate of participation in the SEFFICARE Basic Course. S.E.F.F.I. AND MicroS.E.F.F.I. TISSUE GRAFT – Superficial Enhanced Fluid Fat Injection Since 2015 A. Gennai et al. have been publishing several studies (see references) about the new tissue graft techniques SEFFI and MicroSEFFI. These techniques aim to graft adipose tissue including the stromal fraction (SVF) and the ADSCs Adipose Derived Stem Cells contained therein, in order to achieve a tissue regeneration. The Authors proved that it is possible to harvest tissue using special cannulas with very small side ports holes so as to select small cellular clusters that do not need any kind of manipulation in order to fluidify the tissue. SEFFI and MicroSEFFI are now among the most used techniques intended for regenerating tissues. These techniques are considered minimally invasive surgical procedures; hence they require liposuction skills and surgical facilities. In the light of this evidence, Regenerative Therapy has always been only in the hands of plastic surgeons and not open to other doctors and surgeons without liposuction skills. Dr. Gennai strongly believes that the Autologous Regenerative Therapy should be performed also by Doctors and Surgeons even without any liposuction skills: for this reason, he developed, standardized and patented* a special guide addressed to harvest the tissue in a safe, easy, effective way without any liposuction skill. From this original idea SEFFILINE developed SEFFICARE®: it’s an all-in-one and disposable medical device to allow doctors to perform the autologous regenerative treatment in their facility in a safe, easy, effective way. ____________ *Italian patent WHY SEFFICARE® In order to perform a correct Regenerative Therapy, a SAFE, EASY, EFFECTIVE and STANDARDIZED method is needed to harvest adipose tissue containing the stromal component (SVF) and adult mesenchymal stem cells (ADSCs). This method must have the following characteristics: Tissue harvesting should involve the least possible trauma both for the tissue and the patient; adipose tissue harvesting should occur as close as possible to the skin surface in order to obtain a tissue richer in ADSCs; Cell clusters should be harvested with small size adipocytes, stromal tissue (SVF) and ADSCs to favor their engraftment in the recipient site; The harvested tissue should be manipulated as little as possible in order to preserve the highest cell viability and avoid the use of devices for tissue fragmentation: this will make the method faster and less expensive; The method should be as little traumatic as possible for the patient and minimize harvesting complications such as hematomas, seromas, infections and skin irregularities; The tissue to be engrafted should be sufficiently fluid to be grafted with needles or thin cannulas so as to be as least traumatic as possible for the recipient site. In the technique of preparing the tissue to be engrafted, the harvesting phase is the most difficult one for doctors who do not have a specific preparation in suctioning subcutaneous adipose tissue. Due to this difficulty, very often physicians resort to the aid of specialists in plastic surgery, thus increasing the costs of the procedure and making the organization of the therapy more complex, since it might require several treatments. In some cases, they renounce to regenerative therapy, exposing their patients to possible complications related to incorrect harvesting maneuvers. SEFFICARE® is a sterile disposable “all in one” kit, for regenerative medicine therapy. The kit makes the harvesting, preparation and grafting procedure EASY, SAFE, EFFECTIVE and STANDARDIZED. The scientific contents are edited by Prof. Alessandro Gennai, MD registered in the register of the Medical Association of Modena n ° 4230 (https://www.ordinemedicimodena.it/det...)