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In this video tutorial, we have discussed LOCK AND KEY HYPOTHESIS OF AN ENZYME and it's biochemical properties. The specific action of an enzyme with a single substrate can be explained using a Lock and Key analogy first postulated in 1894 by Emil Fischer. In this analogy, the lock is the enzyme and the key is the substrate. Only the correctly sized key (substrate) fits into the keyhole (active site) of the lock (enzyme). In the next part of this series, we will discuss other topics related to enzymology. People also ask What are the lock and key mechanism? Why was the lock and key model rejected? Who proposed lock and key theory of enzymes? How are the lock and key and induced fit models different? lock and key hypothesis Wikipedia lock and key hypothesis pdf short note on lock and key hypothesis lock and key model example structure of lock and key model lock and key model vs induced fit model discuss the lock and key hypothesis of enzyme activity induced fit hypothesis