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Train our immune system to kill cancer and prevent recurrence | TARGET: Cancer Podcast | Ep. 27 Our guest this week is Dr. Ian Walters, CEO of Portage Biotech. Dr. Juneja talks with Dr. Walters to explain how we can potentially educate our own immune system to kill cancer cells and then retain that education to prevent future recurrences. And what if we could create a drug to impact multiple cancers - via existing checkpoint inhibitors or pathways? Watch this episode to find out about the science that is being developed right now. - - -TimeStamps - - - - 00:00 Introduction 05:13 CTLA-4 - What is it and how it works? 18:06 Microsatellite instability (MSI) 23:56 Making one drug that can impact multiple cancers 41:12 Don't be afraid of clinical trials. It's where you get the best treatment. - - - #cancertreatment #targetcancerpodcast #cancer #immunesystem #targetedtherapy #xcures #theoncdoc #portage 🔴Like, Subscribe, and Share to see more of this type of content! — ABOUT DR. IAN WALTERS — Dr. Ian Walters has over 20 years of leadership and expertise in oncology/immunology drug development and specializes in the evaluation, prioritization and innovation of new therapies for the treatment of severe diseases. Currently, he is the CEO of Portage Biotech. Prior to Portage, Ian spent seven years at Bristol Myers Squibb, where he managed physicians overseeing the international development of more than eight oncology compounds including nivolumab (anti-PD-1), ipilimumab (anti-CTLA-4), brivanib (anti VEGF/FGF), anti-IGF/IR, VEGFR2 biologic, elotuzumab (antiCS1) and biomarker and companion diagnostic work. He was a core member of Bristol Myers Squibb’s Strategic Transactions Group evaluating and executing licensing agreements, mergers and acquisitions, clinical collaborations and the company’s immuno-oncology strategy. Prior to BMS, he held positions at PDL BioPharma, Inc., Millennium Pharmaceuticals, Inc. and Sorrento Therapeutics, Inc., leading corporate development, translational medicine, clinical development and medical affairs. Before entering the private sector, Ian was a lead investigator at the Rockefeller University and initiated advanced immunology research to understand the mechanism of action of several compounds. Ian received his M.D. from the Albert Einstein College of Medicine and an MBA from the Wharton School of The University of Pennsylvania — ABOUT DR SANJAY JUNEJA — Dr. Sanjay Juneja is a triple board-certified Hematologist & Medical Oncologist serving as Chief of Oncology Service at Baton Rouge General Hospital, a social & news media personality known as the 'TheOncDoc' with over half a million followers, and one of fifteen social media doctors participating in the Healthcare Leaders in Social Media Round Table Series for the White House. He has been featured by The Washington Post as well as dozens of national podcasts and regional news channels (PBS, CBS, NBC, NPR), and has given keynote speeches and partnered with American Cancer Society, BeTheMatch, Leukemia & Lymphoma Society, Harvard University, Louisiana Department of Health and several others. — ABOUT xCURES — The xCures platform is a direct-to-patient and direct-to-physician portal that identifies the most promising treatment options for advanced cancer patients who are not responding to standard of care therapies. The platform captures data that also helps accelerate the development of promising new cancer drugs, expand the approved uses of existing drugs, and demonstrate value for reimbursement. Learn more at: https://xcures.com/ Facebook: / xcures.platform TikTok: / xcures.platform Instagram: / xcures.platform LinkedIn: / xcures Twitter: / xcures_platform TARGET: Cancer Podcast Homepage: https://xcures.com/target-cancer-podc... YouTube: / targetcancer Spotify: https://open.spotify.com/show/2xMG5y5... iTunes: https://podcasts.apple.com/us/podcast... TuneIn: https://tunein.com/podcasts/Technolog... Google Podcasts: https://podcasts.google.com/feed/aHR0... Pandora: https://www.pandora.com/podcast/targe... Stitcher: https://www.stitcher.com/show/1022571 Amazon Music: https://music.amazon.com/podcasts/a80...