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Reference: https://www.videogie.org/article/S246... Endoscopic retrograde cholangiopancreatography (ERCP) is a specialized procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions affecting the bile ducts and pancreatic duct. This technique is particularly valuable in managing obstructive jaundice, pancreatitis, and other biliary disorders. The procedure involves the insertion of an endoscope through the mouth, esophagus, and stomach into the duodenum, where the ampulla of Vater is located. Here, contrast dye is injected into the biliary and pancreatic ducts, allowing for imaging via X-ray to identify any blockages, stones, or abnormalities. The use of ERCP has revolutionized the approach to biliary and pancreatic diseases, providing both diagnostic and therapeutic capabilities in a minimally invasive manner. In certain clinical scenarios, particularly when traditional access routes are compromised or when patients have undergone previous surgeries that alter the anatomy, a gastrojejunal lumen-apposing stent can be employed to facilitate ERCP. This stent serves as a conduit between the stomach and the jejunum, allowing for easier access to the duodenum and the biliary tree. The placement of a lumen-apposing stent is particularly beneficial in patients with conditions such as duodenal obstruction or those who have undergone Roux-en-Y gastric bypass surgery, where standard ERCP may be challenging. By creating a direct pathway, the gastrojejunal stent enhances the ability to perform ERCP effectively, ensuring that the necessary interventions can be carried out without the need for more invasive surgical procedures. The integration of a gastrojejunal lumen-apposing stent into the ERCP procedure not only improves access but also enhances patient outcomes by reducing the risk of complications associated with traditional approaches. This technique allows for the successful removal of biliary stones, placement of biliary drains, and management of strictures, all of which are critical in alleviating symptoms and preventing further complications. Moreover, the use of this stent can lead to shorter recovery times and less postoperative discomfort for patients, making it a valuable tool in the endoscopic management of biliary and pancreatic disorders. As advancements in endoscopic technology continue to evolve, the application of such innovative techniques will likely expand, further improving the efficacy and safety of ERCP procedures.