JAX Tech Talk Episode #66: Let’s Talk J:ARC Swiss Outbred Mouse Model скачать в хорошем качестве

JAX Tech Talk Episode #66: Let’s Talk J:ARC Swiss Outbred Mouse Model

July 20th, 2023 – In today’s JAX Tech Talk episode, we revisit the J:ARC Swiss Outbred model. The Swiss Outbred is a well-known outbred mouse model with numerous research applications, ranging from toxicity studies to recipient dams for in vitro fertilization. Along with their many uses, these mice exhibit a high level of heterogeneity at most loci, providing a robust platform of diversity. During this presentation, we will discuss our J:ARC Swiss Outbred model, its origins, considerations for maintaining the diversity in J:ARC colonies, and a recent study quantifying the heterogeneity in this model. Helpful Resources: • Strain Datasheet for J:ARC Swiss Outbred Mice: https://www.jax.org/strain/034608 • Video recording of a previous (2021) JAX Tech Talk on JAX Swiss Outbred Mice: https://resources.jax.org/jax-tech-ta... • Publication: “Protein coding variation in the J:ARC and J:DO outbred laboratory mouse stocks provides a molecular basis for distinct research applications” (April 2023): https://pubmed.ncbi.nlm.nih.gov/36649... • Diversity Mice User Guide: https://resources.jax.org/jax-blog/di... • MiniCourse: Mouse Genetic Diversity: Translating Discoveries to Humans: https://education.learning.jax.org/mo...