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Jeffrey M. Holzbeierlein, MD, Director of the Division of Urologic Oncology at the University of Kansas Hospital and Director of Clinical Research for the Urology Department at KUMC, discusses the role of immunonutrition in bladder cancer. He highlights some of the research showing why nutrition should play an important role in improving outcomes for radical cystectomy, a treatment for bladder cancer that is underutilized due to the high number of poor outcomes. Dr. Holzbeierlein goes on to discuss the SIMMUNE trial (S1600), which he is leading at the KU Medical Center. In the pilot, they gave patients a specialized immunomodulating drink, which Dr. Holzbeierlein emphasizes is a commercially available drink that patients can purchase themselves online, prior to surgery. He outlines the methods of the study as well as the results and the conclusions that were drawn. Finally, Dr. Holzbeierlein stresses that this is an easy intervention that most doctors could implement immediately.