FOLFOX / XELOX Side Effects - Colon Cancer скачать в хорошем качестве

FOLFOX / XELOX Side Effects - Colon Cancer

Front line therapy for respected colon cancer or colon cancer that has spread to other parts of the body is often treated with FOLFOX or CAPOX. The 5-FU (a fluoropyrimidine drug) often has various side effects, such as nausea, vomiting, diarrhea, and low blood counts. Oxaliplatin can cause cold hypersensitivity, neuropathy, extravasation, and allergic reactions. It is advised to limit cumulative exposure to oxaliplatin. More videos like this: https://ruesch.georgetown.edu/rueschr... Transcript: Frontline therapy for resected colon cancer or colon cancer that has spread to other parts of the body includes a combination of drugs that is commonly referred to as either a FOLFOX or a CAPOX. FOLFOX uses a pump form of an IV drug called fluorouracil, as well as a drug called oxaliplatin and a vitamin called leucovorin. CAPOX uses a pill version of the pump drug, capecitabine, in combination with oxaliplatin. The fluoropyrimidine drug whether it's in the pump form or the pill form has unique potential side effects. These include low blood counts, fatigue, nausea, vomiting, diarrhea, and mucositis, which is inflammation anywhere along the GI tract but may manifest itself as mouth sores. Oxaliplatin can cause numbness and tingling in the hands and feet, both a cold sensitivity which occurs with each dose, as well as a cumulative nerve toxicity that leads us to stop the drug at some point. Another rare potential side effect of 5-fluorouracil is coronary vasospasm which can feel like a heart attack and if you experience any new or sudden chest discomfort, you should go to the emergency room and alert the physicians that you are on either 5-fluorouracil or capecitabine.