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Topoisomerase 1 and 2 mechanism

Topoisomerase 1 and 2 - This lecture explains about the topoisomerase 1 and 2 mechanism of action. Topoisomerase 1 enzyme cleaves single strand of the DNA and can change the DNA linking number while the topoisomerase 2 can relax the DNA by creating negative supercoiling by cleaving both the DNA strands at the same time. This video lecture explains about the topoisomerase 1 mechanism and the topoisomerase 2 mechanism to relax the DNA by changing the DNA super coiling. Type II topoisomerase cuts both strands of one DNA double helix, passes another unbroken DNA strand through it, and then reanneals the cut strand. Both type 1 and type 2 topoisomerase are of 2 types. For more information, log on to- http://www.shomusbiology.com/ Get Shomu's Biology DVD set here- http://www.shomusbiology.com/dvd-store/ Download the study materials here- http://shomusbiology.com/bio-material... Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology- Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching We are social. Find us on different sites here- Our Website – www.shomusbiology.com Facebook page-   / shomusbiology   Twitter -   / shomusbiology   SlideShare- www.slideshare.net/shomusbiology Google plus- https://plus.google.com/1136485849827... LinkedIn -   / suman-bhattacharjee-2a051661   Youtube-    / thefunsuman   Thank you for watching the video lecture on Topoisomerase 1 and 2.