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Understand Early Pregnancy Physiology with Dr. Faiza Dive into a clear, step-by-step explanation of oocyte maturation, fertilization, and early embryo transport before implantation. This session covers meiotic divisions, the acrosome reaction and polyspermy block, tubal transport mechanisms, hormonal support from the corpus luteum, and the timing from ovulation to uterine entry—perfect for students preparing for exams in physiology and reproduction. Personal Stamp: Presented by Dr. Faiza 🔬 Key Topics Covered: Oocyte Maturation: From primary oocyte (prophase I arrest) to secondary oocyte and ovum; polar bodies and chromosomal counts (46→23). Fertilization Site & Steps: Ampullary region, sperm capacitation, GP3 binding on zona pellucida, acrosome reaction, membrane fusion. Polyspermy Prevention: Cortical granule release, zona/ membrane changes, membrane potential shift. Tubal Transport: Ciliary action, oviduct smooth muscle contractions, roles of estrogen, progesterone, prostaglandins, and oxytocin. Embryo Progression: Zygote → morula en route to uterus; uterine secretions (“uterine milk”) and tubal secretions as interim nutrition. Timing & Regulation: 3–5 days to reach the uterus; isthmic delay and subsequent progesterone-mediated relaxation; overview of implantation window. Hormonal Support: Corpus luteum function after ovulation and its role in sustaining early pregnancy. 🎓 Learning Objectives: Trace chromosome and cell-state changes from primary oocyte to fertilized ovum. Explain the acrosome reaction and mechanisms preventing polyspermy. Describe how cilia, smooth muscle, and hormones coordinate embryo transport. Outline the timeline from ovulation to uterine entry and pre-implantation nutrition. Relate corpus luteum function to early pregnancy maintenance. 📚 Learning Resources: Phone: +92 310 7990649 Email: [email protected] Website: https://www.medicoseacademics.com/ Facebook: / medicoseacademics Instagram: / medicoseacademics YouTube: / @medicoseacademics Dr. Faiza Assistant Professor of Physiology MBBS (AIMC, lahore, Best Graduate) FCPS (Physiology) CHPE (Certificate in Health Professional Education) DHPE (Diploma in Health Professional Education) DHPE (Masters in Health Professional Education) MBA (Masters of Business Administration) MPH (Masters of Public Health) LinkedIn: / faizaikram Tags: Pregnancy Physiology, Oocyte Maturation, Meiosis, Fertilization, Acrosome Reaction, Zona Pellucida, Polyspermy Block, Fallopian Tube, Ampulla, Ciliary Action, Corpus Luteum, Estrogen, Progesterone, Embryo Transport, Uterine Milk, Implantation Window, Chemotaxis, Prostaglandins, Oxytocin, Female Reproductive Physiology