Apoptosis Regulation by Genes | Bcl-2 Family скачать в хорошем качестве

Apoptosis Regulation by Genes | Bcl-2 Family

In this video we have discussed the regulation of Apoptosis by genes. The Apoptosis is regulated by various genes but Bcl family of genes are the primary regulators of the apoptosis. Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a form of programmed cell death that occurs in multicellular organisms.[2] Biochemical events lead to characteristic cell changes (morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, chromosomal DNA fragmentation, and global[vague] mRNA decay. The initiation of apoptosis is tightly regulated by activation mechanisms, because once apoptosis has begun, it inevitably leads to the death of the cell. The two best-understood activation mechanisms are the intrinsic pathway (also called the mitochondrial pathway) and the extrinsic pathway.