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Imagine you’re a scientist trying to study how plants respond to environmental stress. You want to see how long-term drought conditions affect certain cell membrane structures, but doing it manually would take months and months of work, and you lack the skills to build a computer algorithm that could do it for you. This is exactly what the BioImage Model Zoo, a community-driven repository of pre-trained, deep-learning models, helps to solve. The Zoo is one of the core facets of AI4LIfe, which aims to bring together the computational and life sciences communities by making AI models more accessible and easy to use. BioImage Model Zoo began over three years ago as a collaboration between EMBL Group Leader Anna Kreshuk, Wei Ouyang, a SciLifeLab fellow and an assistant professor at KTH Royal Institute of Technology, and Florian Jug, a computational biologist and Senior Group Leader at the Human Technopole Foundation. As scientific coordinators of AI4Life, Kreshuk and Jug work together with other partners across Europe, including the project's main coordinator Euro-BioImaging. The first phase of AI4Life, which began in 2022, ended in August 2025, so we caught up with Kreshuk and Jug to learn more about the project, its use, and what they hope its impact will be. *** AI4Life has received funding from the European Union’s Horizon Europe research and innovation programme under grant agreement number 101057970. AI4Life is made possible thanks to support from its community and project partners. Its community partners include Bioimage.io, ZeroCostDL4Mic, deepImageJ, Fiji, ImJoy, Ilastik, and the Human Protein Atlas (HPA). Project partners include EMBL, EMBL-EBI, EMBRC, EMPHASIS, Euro-BioImaging, EU Open Screen, Human Technopole, Instituto Gulbenkian De Ciéncia, Instruct ERIC, KTH, and Universidad Carlos III de Madrid. *** Read more about AI at EMBL: https://www.embl.org/topics/ai-at-embl/ Read more about AI4Life: https://ai4life.eurobioimaging.eu/abo... Video producer and Editor: Sera Guli/EMBL Interview footage: Ivy Fleischer Kupec, Shreya Ghosh and Sera Guli/EMBL Images: Holly Joynes and Isabel Romero Calvo/EMBL Music: Eco Technology by Aleksey Chistilin from Pixabay © European Molecular Biology Laboratory (EMBL)