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Multiple myeloma is a hematologic malignancy characterized by abnormal plasma cells in the bone marrow, with potential uncontrolled growth causing destructive bone lesions, kidney injury, anemia, and hypercalcemia. Edward Libby, MD, of the University of Washington, joins JAMA Associate Editor Ethan Basch, MD, of the University of North Carolina, for a discussion of the diagnosis, complications, and management of myeloma, as well as the related conditions of monoclonal gammopathy of undetermined significance (MGUS) and smoldering myeloma. Related Content: Diagnosis and Management of Multiple Myeloma https://ja.ma/45qjSBl Patient Information: Multiple Myeloma https://ja.ma/45pF8qY Podcast was originally published on February 1, 2022. https://edhub.ama-assn.org/jn-learnin... --------------------------------------------------------------------------------- Follow JAMA Clinical Reviews on: Youtube: • JAMA Clinical Reviews Apple Podcasts: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/229VuDi... Pocket Casts: https://pca.st/3ghw Your podcast app of choice: https://pod.link/1027430378 Website: https://jamanetwork.com/journals/jama... --------------------------------------------------------------------------------- For more from JAMA • https://www.jama.com • / jamajournal • / jama_current • / jamanetwork Follow the JAMA Network • https://www.jamanetwork.com • http://www.jamanetworkaudio.com • / jamanetwork • / jamanetwork • / jamanetwork • / jamanetwork