Autism Metabolomics, Exposomics & Purinergic Stress Response - R. Naviaux MD @SynchronySymposium2020 скачать в хорошем качестве

Autism Metabolomics, Exposomics & Purinergic Stress Response - R. Naviaux MD @SynchronySymposium2020

What do you find when you look for 1000 environmental chemicals in children with Autism Spectrum Disorder? Do children with autism react differently than children without ASD to the same environmental chemicals? How can this be measured? How does the rising tide of manmade chemicals in our food chain, water, and air change the chemistry of children with and without ASD? What happens when stressed cells leak ATP? In this talk Synchrony 2020 titled ‘Autism Metabolomics, Exposomics, and the Purinergic Stress Response’, Dr. Naviaux reports on his latest data that aims to answer these questions. Robert Naviaux MD, PhD is a Professor of Genetics, in the Departments of Medicine, Pediatrics, and Pathology. He directs a core laboratory for metabolomics at UCSD. He is the co-founder and a former president of the Mitochondrial Medicine Society (MMS), and a founding associate editor of the journal Mitochondrion. Dr Naviaux is an internationally known expert in human genetics, inborn errors of metabolism, metabolomics, and mitochondrial medicine. He is the discoverer of the cause of Alpers syndrome—the oldest Mendelian form of mitochondrial disease – and the developer of the first DNA test to diagnose it. Dr.Naviaux’s lab has developed a number of advanced technologies like biocavity laser spectroscopy and mtDNA mutation detection by mass spectrometry. He is a Salk-trained virologist, and molecular and cell biologist, the inventor of the popular pCL retroviral gene transfer vectors, and was trained at NIH in tumor immunology and natural killer cell biology. He studied biochemistry at Georg-August University in Göttingen, Germany. He has been the PI for over 20 IRB-approved human subjects protocols at UCSD since 1995. In 2010, Dr. Naviaux was a member of the Cal-Echoes oceanographic expedition to collect environmental and ecosystem data along the California coast. His work in ecosystem dynamics has guided new work in microbiome ecology and metabolism in autism spectrum disorders. In 2011, he received a Trailblazer Award from Autism Speaks. He is currently the director of the first FDA-approved clinical trial to study the safety and test the effects of suramin on behavior and language in children with autism. #suramin #purinergic #biology #cellularbiology #metabolism #research #medicalscience #braindevelopment #environment 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 Synchrony https://synchronysymposium.com/ is the first and only international symposium on translational research in #autism, that brings together academia, #biotech, pharmaceutical companies and #venture partners from around the world with the mission to improve health and quality of life of people with #autismspectrumdisorder 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 🧠 The BRAIN Foundation https://brainfoundation.org/ is a 501c(3) non-profit. The founders of BRAIN envision a world where every child and adult on the autism spectrum is healthy, participates fully in education and employment, and has a better quality of life. It aims to catalyze research that results in evidence-based interventions for the disabilities associated with autism, and also results in better medical standard of care. To accomplish this, it funds impactful research through #philanthropy and our network of partners in the venture, corporate, and grassroots community.