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In this video, Andie MacAndrew, a first-year Master’s student in Dr. Cindy Braha’s lab at McMaster University, dives into the fascinating and critical topic of how cannabis affects neuroplasticity and fetal brain development. With anxiety and depressive disorders on the rise, many adults—including pregnant women—are turning to cannabis as a form of self-medication. However, the impact of cannabis on neurodevelopment, particularly during pregnancy, remains poorly understood. Andie’s research focuses on the effects of THC and CBD on hippocampal neurogenesis and mitochondrial dynamics, shedding light on how prenatal cannabis exposure may lead to long-term changes in brain function and behaviour. Using both in vivo and in vitro models, Andie’s study explores how cannabis exposure during early pregnancy alters fetal brain development, with a particular focus on markers of neurogenesis and mitochondrial function. The research also investigates how stress hormones like corticosterone interact with cannabinoids to influence these processes. This groundbreaking work aims to uncover the mechanisms behind cannabis-induced neuroplastic changes and their potential implications for mental health outcomes in offspring. Join us as we delve into the science behind cannabis, neurodevelopment, and mental health. Whether you’re a student, researcher, or simply curious about the effects of cannabis on the brain, this video offers valuable insights into one of the most pressing topics in neuroscience today. A presentation for the Innovations in the Science of Cannabis Conference, May 2022 ___________________________________ cannabis and fetal brain development THC CBD neuroplasticity prenatal cannabis exposure effects cannabis and neurogenesis cannabis during pregnancy risks hippocampal neurogenesis cannabis mitochondrial dynamics cannabis cannabis and mental health cannabis research 2023 stress hormones and cannabis cannabis and anxiety disorders fetal development and THC CBD and brain health cannabis neuroscience research cannabis and mitochondrial function ______________________________