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Watch the Full Video at https://www.jove.com/v/52382/facial-n.... Facial Nerve Axotomy in Mice: A Model to Study Motoneuron Response to Injury - a 2 minute Preview of the Experimental Protocol Deborah N. Olmstead, Nichole A. Mesnard-Hoaglin, Richard J. Batka, Melissa M. Haulcomb, Whitney M. Miller, Kathryn J. Jones Indiana University School of Medicine, Anatomy and Cell Biology; Richard L. Roudebush VA Medical Center, Research and Development Services; University of Illinois, Chicago, Department of Anatomy and Cell Biology; We present a surgical protocol detailing how to perform a cut or crush axotomy on the facial nerve in the mouse. The facial nerve axotomy can be employed to study the physiological response to nerve injury and test therapeutic techniques. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments