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This video is appropriate for those that have been prescribed opioids for managing chronic pain or those who have been prescribed opioids for over two weeks, even for those who have been taking opioids for months and even years (as medicine is constantly changing). There are new federal and state requirements (such as the Opioid Agreement) as the risks become greater when opioids are taken long-term. Six tips to keep everyone safe (including your family pets) are shared, along with the need for compliance and signs of opioid misuse. The benefits of taking opioids and setting goals of therapy are also considered. If you feel that you are experiencing the warning signs of addiction, please talk to your clinician as there are ways to treat opioid addiction, which can be a complication from taking opioids even as prescribed for some patients. Another valuable resource is to call the Substance Abuse and Mental Health Services Administration’s (SAMHSA’s) Helpline at 1-800-662-HELP (4357), which is available 24 hours per day, 7 days per week. Please fill your prescription for Narcan® (naloxone HCI) nasal spray once a year, which can reverse an opioid overdose. Naloxone saves lives!