Causes and Consequences of LUTO (2 of 9) скачать в хорошем качестве

Causes and Consequences of LUTO (2 of 9)

The impact a lower urinary tract obstruction has on a developing fetus depends on how significant the obstruction is and how early it occurs. http://fetalsurgery.chop.edu Lower urinary tract obstructions (LUTO) occur in utero as a result of an obstruction of the urethra that restricts the passage of urine. Experts from the Fetal Diagnosis and Treatment at Children's Hospital of Philadelphia talk about the consequences of continued obstruction that can lead to underdeveloped lungs and impaired kidney (renal) development and function. LUTO is a very rare anomaly. Obstructions to the urethra come in many different forms, ranging from a flap of tissue called posterior urethral valve; to a complete obstruction where the tube of the urethra never connects, called a urethral atresia; or a constricted urethral narrowing that makes it difficult to pass urine. The more significant the obstruction, and the earlier it occurs, the more serious impact it has on the developing fetus. One problem in LUTO is that the baby is unable to maintain a sufficient volume of amniotic fluid because they continue to ingest the fluid but can’t pass urine to replace the amniotic fluid. When the volume of amniotic fluid gets very low (oligohydramnios), it can cause serious problems with lung development and result in pulmonary hypoplasia (underdeveloped lungs) and kidney damage.