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In this video, I'll take you through the production of an actual cell product (insulin) to demonstrate how the cell is like a factory. We'll see how pancreatic beta cells TRANSCRIBE the INS gene, how ribosomes TRANSLATE that mRNA into preproinsulin, how the rough ER turns preproinsulin into proinsulin and how the Golgi (at last!) completes the final activation step to produces the final, functional hormone INSULIN. We'll have penguins and analogies along the way of course! #anatomyandphysiology #emtstudent #paramedicstudent #nursingstudent #cell #biology #biologystudents This video supports selected content in: OpenStax Anatomy and Physiology 2e, section 3.4 OpenStax Concepts of Biology, sections 9.3 and 9.4 OpenStax Biology 2e, sections 15.1, 15.3, 15.5 Video Chapters: Intro: 0:00 No magic, only mechanism: 0:33 Penguin analogy: 0:41 Standardized nomenclature: 1:09 Transcription and translation - major players: 2:55 Transcription: 3:08 Transcription practice: 4:04 Translation: 5:05 Translation table: 5:27 Translation wheel: 5:57 Translation practice: 6:12 Preproinsulin signal peptide cleavage in rER: 6:52 Proinsulin final cleavage to make insulin in Golgi: 7:10 Insulin structure: 7:20 Summary: 7:49 Outro: 8:37 Videos mentioned: Your Blood Sugar: Insulin and Glucagon: • Your BLOOD SUGAR: Insulin and Glucagon 🐧 How Insulin Causes Blood Glucose Uptake: • How INSULIN Causes Glucose Uptake | Physio... Animal Cells: What You NEED to Know: • Animal Cells: What You NEED to KNOW! | Bio... Penguin Prof Staff: Organic chemistry consultant in residence: FabioChem (Fabio Agnelli, Ph.D) Happiness Coordinator: Flops the Penguin Content Creator, Producer, Editor and Narrator: The Penguin Prof (Valerie Pennington) Let's Connect! https://hihello.me/hi/penguinprof-U55i9g Want more Penguin Prof? Subscribe: / thepenguinprof FB Page: / thepenguinprof Instagram: / penguinprof TikTok: / penguinprof Twitter: / penguinprof Web: http://www.penguinprof.com/ LinkedIn: / penguinprof Other Videos You May Enjoy: Your Heart: • The HEART | A&P Basics ❤️🐧❤️ Your Capillaries: • Capillaries and Capillary Exchange | A&P B... Your Bones: • Intro Skeleton and Bone Tissue | A&P Basic... Take Great Notes: • Take GREAT Notes -- That Help You LEARN! Should You Use Your Textbook? • Should You USE Your Textbook? Study Skills 🐧 Enzyme Regulation Explained: • Enzyme Regulation EXPLAINED! 🐧 Homeostasis and Feedback: • Homeostasis and Feedback | Physiology 🐧 Levels the Protein Structure: • Amino Acids and Levels of Protein Structure How Hormones Work: • How Hormones Work: An Easier Approach to ... Chemistry Basics Part I: • Basic Chemistry Concepts Part I 🐧 Chemistry Basics Part II: • Atomic Bonds - Chemistry Basics Part II 🐧 Understanding Chemical Structures: • Making Sense of Chemical Structures | Chem... Blood Types: ABO and Rh: • ABO and Rh (blood types with donuts!) | Ph... All Rights Reserved © 2025, The Penguin Prof Affiliate Links Below you'll find a list of products or services that I truly believe in, support and pay for. If you click them, a small amount of change goes to support this channel. Rocketbook: Use and re-use paper, scan and digitize everything and send your stuff wherever you need it: [[https://bit.ly/3wv9ZkJ](https://bit.ly/3wv9ZkJ)] Penguin Prof is Supported by Audible! I've been an Audible addict since 2013. Audible is the premier provider of digital audiobooks. Audible has over 150,000 titles to choose from in every genre. Audible titles play on iPhone, Kindle, Android and more than 500 devices for listening anytime, anywhere. Click to learn more and download a FREE audiobook of your choice! http://www.audibletrial.com/PenguinProf Discounts for Camtasia (my favorite video editor) and Snagit (my favorite screen annotation software): https://techsmith.z6rjha.net/5bDN1o Descript: Simply the EASIEST and FASTEST way to produce transcripts and captions for your videos: https://www.descript.com/?lmref=diMR8w Royalty-Free Music by Epidemic Sound If you're looking for an amazing library of royalty-free music, as well as over 60,000 sound effects, look no further than Epidemic Sound. I've been a member for years and I love being able to find the perfect track for every project. Help support my channel if you're interested and sign up with this link: https://www.epidemicsound.com/referra... GEAR: Mic: Apogee HypeMic Computer: Apple Mac mini (M1, 2020) SOFTWARE: Camtasia Descript (for subtitles and transcripts)