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A Rathke's cleft cyst is a benign, fluid-filled cyst that forms in the pituitary gland. It arises from the remnants of Rathke's pouch, an embryonic structure that normally regresses during fetal development2. Here are some key points about Rathke's cleft cyst: Characteristics Location: Typically found in the sellar or suprasellar region of the brain. Contents: The cyst is filled with mucin-like fluid. Size: Can range from 2 to 40 mm in diameter. Symptoms Asymptomatic: Many Rathke's cleft cysts are incidentally found and do not cause symptoms. Headaches: When symptomatic, they can cause persistent headaches. Visual Disturbances: Large cysts can compress the optic chiasm, leading to visual field defects such as bitemporal hemianopsia (loss of peripheral vision). Hormonal Imbalance: Compression of the pituitary gland can lead to hormonal imbalances, causing symptoms like fatigue, weight changes, and menstrual irregularities. Diagnosis Imaging: Diagnosed through imaging studies such as MRI, which reveal the cyst's location and size1. Endocrinological Assessment: Hormonal evaluations may be conducted to assess pituitary function. Treatment Observation: Small, asymptomatic cysts may be monitored without intervention. Surgery: Symptomatic cysts, especially those causing visual or hormonal disturbances, may require surgical removal or drainage. Would you like more detailed information on any specific aspect of Rathke's cleft cysts? #Rathkecleft