Nano-functionalized Stents in the Esophagus and the Upper Gastrointestinal Track скачать в хорошем качестве

Nano-functionalized Stents in the Esophagus and the Upper Gastrointestinal Track

Bare metallic stent placement in patients with benign esophageal strictures is a relative contraindication. Temporary stent placement is safe and useful, but with high recurrence rates in benign esophageal strictures. Tissue hyperplasia represents a major limitation to long-term stent placement in the esophagus. Selective ALK-5 inhibitor eluting stents and siRNA therapy have therapeutic potential in the prevention and treatment of tissue hyperplasia secondary to stent placement in the esophagus. 1. Start 00:00 2. 1st. Q&A 24:55 3. 2nd. Q&A 28:28 Moderate local heating with nano-functionalized stents represents a promising new approach for suppressing stent-induced tissue hyperplasia in the rat esophagus. BGNP-coated nitinol stent is excellent in heat generation by NIR laser irradiation, and the PT property can be easily controlled by adjusting the NIR laser power. HSP70 expression increased after heating, strongly correlated with cell apoptosis and inversely correlated with cell proliferation including cell cycle markers (Ki67 and BrdU).