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The safety of microbially-derived food enzymes must be carefully assessed, notably the production strain’s safety. The concept of Safe Strain Lineage is explained in this video, and two Safe Strain Lineages developed by DSM are presented. This approach enables a thorough safety assessment of food enzymes, with less animal sacrifice and less data to evaluate. Did you enjoy Melina Galano's video? Sign in to YouTube with your Google account and give it a thumbs up! This video is part of the ONE – Health, Environment, Society – Conference 2022 video contest, running from 1 to 28 February. Poster presenters are showcasing their research in short YouTube videos for the chance to win a trip to Brussels to deliver a live pitch at the conference in June. The three most-liked videos will be the winners. More contest videos: https://bit.ly/ONEcontest About the One Conference 2022: Co-organised by EFSA and other European scientific agencies, the conference will bring together speakers and participants from diverse backgrounds to discuss food/feed safety and developments in risk assessment science. Brussels & online | 21-24 June https://www.one2022.eu/ #OneEU2022 #enzymesafety #strainlineage #ecdc #FoodSafety