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Title: Prognostic Modeling for Pediatric Obesity Prevention Including the Role of Leukocyte Telomere Length - Frontiers in Child Health Research Seminar Speaker: Janet Wojcicki, PhD, MPH Professor, Pediatrics and Epidemiology Division of Gastroenterology, Nutrition, and Hepatology UCSF Department of Pediatrics Can we predict and prevent pediatric obesity by identifying high-risk infants in their first few months of life? Explore the cutting edge of prevention science with Dr. Janet Wojcicki, an anthropologist and epidemiologist who brings a unique interdisciplinary approach to understanding early life risk factors and pediatric metabolic health outcomes. With over 130 publications, she is a leading expert in maternal exposure during pregnancy and early-life feeding decisions that can increase obesity risk. This Frontiers in Child Health Research seminar dives into the power of prognostic models, focusing on one developed here in San Francisco from a Latino mother-child cohort. Dr. Wojcicki discusses how this model, using data from the first six months of life, has been successfully applied to predict obesity in a wide range of populations, including two multi-ethnic urban cohorts and a rural Mexican American group. Further, she discusses a potential novel predictor in these critical early stages: leukocyte telomere length. Learning Objectives: •Describe how prognostic models can be used to prevent childhood obesity by collecting data in the first 6 months of life. •Discuss one prognostic model developed in SF that has been used in different settings in the United States and Japan to predict childhood obesity by 5 years of age. •Introduce the possible role of leukocyte telomere length as a predictor of childhood obesity.