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Watch the Full Video at https://www.jove.com/v/57557/a-drosop.... A Drosophila In Vivo Injury Model for Studying Neuroregeneration in the Peripheral and Central Nervous System - a 2 minute Preview of the Experimental Protocol Dan Li, Feng Li, Pavithran Guttipatti, Yuanquan Song The Children's Hospital of Philadelphia, Raymond G. Perelman Center for Cellular and Molecular Therapeutics; University of Pennsylvania, Department of Pathology and Laboratory Medicine; Here, we present a protocol using the Drosophila sensory neuron - dendritic arborization (da) neuron injury model, which combines in vivo live imaging, two-photon laser axotomy/dendriotomy, and the powerful fly genetic toolbox, as a platform for screening potential promoters and inhibitors of neuroregeneration. Visit https://www.jove.com?utm_source=youtu... to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel: / jovejournalofvisualizedexperiments