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This webinar was presented on June 19, 2018. Click here to access the tool: http://www.nccmt.ca/knowledge-reposit... AMSTAR 2: Appraisal tool for systematic reviews of randomized and observational studies (non-randomized studies) AMSTAR (A MeaSurement Tool to Assess systematic Reviews), originally created in 2007, dealt with critical appraisal of systematic reviews. Since then, there has been a shift in focus toward evidence-informed decision making using a broader scope of evidence, including observational studies or non-randomized studies. AMSTAR 2, an update to the original AMSTAR tool, was created to address the contemporary need for clinical and policy decision making that accounts for real-world observational evidence. How can AMSTAR 2 help you? AMSTAR 2 is practical for use by health professionals and public health practitioners involved in appraising research evidence from a clinical, public health or policy standpoint. Managers and decision makers should also be familiar with the components of the appraisal tool when they are using systematic reviews to inform the basis of evidence-informed decision making. The goal of AMSTAR 2 is to increase its applicability to include critical appraisal of a broad range of study designs on healthcare interventions used in systematic reviews. The National Collaborating Centre for Methods and Tools (NCCMT) is funded by the Public Health Agency of Canada and affiliated with McMaster University. The views expressed herein do not necessarily represent the views of the Public Health Agency of Canada. NCCMT is one of six National Collaborating Centres (NCCs) for Public Health. The Centres promote and improve the use of scientific research and other knowledge to strengthen public health practices and policies in Canada.