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✅ Get the Pulse Weekly (free): https://clearcardio.com/newsletter 📅 Book a ClearCardio consultation: https://clearcardio.com/2025-schedule... Can you have major plaque with great labs, no symptoms, and “no risk factors”? In this episode of Power of Prevention, Dr. Jon Osborne spoke with Tim Ritter to talk about two worlds that overlap more than most people realize: cutting-edge GI clinical trials (Crohn’s + ulcerative colitis, plus metabolic liver disease) and Tim’s own unexpected heart-disease discovery—why tracking plaque over time can change how prevention is managed. You’ll learn: ✅ How IBD care has evolved from “steroids + surgery” to targeted therapies ✅ What it’s like to run large, patient-focused clinical trial networks ✅ Why “Smurfs” can still develop heart disease without classic risk factors ✅ How a high calcium score shifted Tim’s prevention plan ✅ Why tracking plaque over time can reveal what labs alone can’t 🔗 Links • Podcast hub: https://clearcardio.com/podcast • Newsletter: https://clearcardio.com/newsletter • Book a consult: https://clearcardio.com/ Follow ClearCardio: • Instagram: / clearcardio • Facebook: / 61569935527337 • LinkedIn: / clearcardio-llc Connect with the hosts: • Dr. Jon Osborne: / john-osborne-md-phd-facc-fnla-32139223 • Dr. John-David Enright: / john-david-enright-sr-aa865755 Chapters 00:00:00 — Tim Ritter joins + “under height” opener 00:04:00 — Why Tim focuses only on Crohn’s + ulcerative colitis 00:06:00 — Building a national clinical trials network 00:08:30 — “The future is already here” (clinical trials mindset) 00:10:00 — Why IBD meds keep getting safer + more effective 00:12:20 — “I thought I didn’t need to worry about my vascular system” 00:14:10 — Smurfs: no classic risk factors… still plaque 00:15:20 — The calcium score shock 00:17:10 — CTA + AI plaque quantification (baseline) 00:19:10 — When labs look great… but plaque worsens 00:22:00 — “Hot off the press” prevention tools discussion 00:24:30 — Inflammation angle (colchicine) + trend improves 00:27:30 — Wrap + The Gut Doctor mention #cleerly #preventivecardiology #calciumscore #hearthealth #IBD #crohnsdisease #ulcerativecolitis #clinicaltrials #metabolichealth #fattyliver #patientadvocacy