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Support the channel by joining our newsletter: https://bit.ly/watchclockwork How does your DNA contribute to aging? This video provides a really broad introduction to the end replication problem, telomeres and senescence. but can't hit all the important details. Corrections, clarifications and sources are here: https://bit.ly/clockworkep4 Fact-checking for this episode was generously donated by the BRILLIANT @Astroboi on discord (check out his lecture channel here: https://bit.ly/astrolecture Sources are cited in this ever-growing Twitter thread: https://bit.ly/telomeresources This channel is created with the support of all our patrons on Patreon: / clockworkshow Support the channel directly with a one time donation: https://www.paypal.me/clockworkshow This channel is dedicated to sparking your curiosity about biochemistry, not to being a definitive resource. To help you continue you biochem journey, I'm really excited to partner with Biocord , a Discord server dedicated to bringing together biologists from around the globe! Join the conversation with over a thousand life sciences professionals and enthusiasts here:- / discord All music is by Jeremy Blake( / redmeansrecording , released on the Youtube Audio Library. Intro music: Let's Go Home (https://bit.ly/rmrlgh) Outro music: Lost and Found (https://bit.ly/rmrlnf) The style of this video was largely developed based on tutorials by Ben Marriot: (https://bit.ly/posterizethis) Learn more about telomerase and DNA in my post on the subject here: https://bit.ly/clockworkep4